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Figure 5 | Cancer Cell International

Figure 5

From: PBK/TOPK mediates geranylgeranylation signaling for breast cancer cell proliferation

Figure 5

PBK is the YAP target gene in breast cancer MDA-MB-231 cells. The YAP shRNA and the lentiviral vector pLKO.1 stable cell lines were established in MDA-MB-231 cells. The cells were cultured to 90% confluence for extraction of RNA and protein. YAP mRNA and PBK mRNA were detected by PT-PCR (in A and B). The PBK protein level was detected by immunoblotting of the cell lysates (in C).

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