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Table 5 Genotype frequencies in healthy control subjects in this study and from the HapMap project or previous studies

From: Interferon gamma polymorphisms and hepatitis B virus-related liver cirrhosis risk in a Chinese population

SNPs

Number

Genotype frequency

P

Allele frequency

P

+874 T/A

 

AA

AT

TT

 

A

T

 

This study

173

116 (67.1)

47 (27.2)

10 (5.8)

1Ref

279 (80.6)

67 (19.4)

1Ref

Korea [20]

201

151 (75.1)

47 (23.4)

3 (1.5)

0.043

249 (82.5)

53 (17.5)

0.553

Brazil [18]

202

79 (39.1)

82 (40.6)

41 (20.3)

0.000

240 (59.4)

164 (40.6)

0.000

India [15]

146

52 (35.6)

77 (52.7)

17 (11.6)

0.000

181 (62.0)

111 (38.0)

0.032

Tunisia [19]

103

33 (32.0)

47 (45.6)

23 (22.3)

0.000

113 (54.9)

93 (45.1)

0.000

+2109A/G

 

AA

AG

GG

 

A

G

 

This study

173

112 (64.7)

52 (30.1)

9 (5.2)

1Ref

232 (67.6)

111 (32.4)

1Ref

HCB

45

21 (46.7)

18 (40.0)

6 (13.3)

0.040

60 (66.7)

30 (33.3)

0.008

JPT

44

16 (36.4)

13 (29.5)

15 (34.1)

0.000

45 (51.1)

43 (48.9)

0.000

CEU

58

23 (39.7)

31 (53.4)

4 (6.9)

0.003

77 (66.4)

39 (33.6)

0.003

YRI

59

47 (79.7)

12 (20.3)

0 (0)

0.050

106 (89.8)

12 (10.2)

0.013

  1. HCB Han Chinese in Beijing, China, JPT Japanese in Tokyo, Japan, CEU Utah residents with Northern and Western.
  2. European ancestry, YRI Yoruba in Ibadan, Nigeria.