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Figure 1 | Cancer Cell International

Figure 1

From: The role of death-associated protein 3 in apoptosis, anoikis and human cancer

Figure 1

Schematic representation of the relation of DAP3 and DELE with Fas receptor related DISC. AKT/PKB: protein kinase B, CARD: caspase activation and recruitment domain, DAP3: death-associated protein 3, DD: death domains, DED: death effector domains, DELE: death ligand signal enhancer, DR: death receptor, DISC: death inducing signalling complex, FADD: Fas Associated Death, FLICE: FADD-like interleukin-1 beta-converting enzyme, FLIP: FLICE inhibitory protein.

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