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Figure 2 | Cancer Cell International

Figure 2

From: The role of death-associated protein 3 in apoptosis, anoikis and human cancer

Figure 2

General scheme illustrating the internal, external and perforin/granzyme pathways within apoptosis, including the sub-programmes specific to anoikis and DAP3. AKT/PKB: protein kinase B, CARD: caspase activation and recruitment domain, DAP3: death-associated protein 3, DD: death domains, DED: death effector domains, DELE: death ligand signal enhancer, DR: death receptor, DISC: death inducing signalling complex, FADD: Fas Associated Death, FLICE: FADD-like interleukin-1 beta-converting enzyme, IPS: 1interferon-β promoter stimulator 1.

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