Impact of ABCG2 polymorphisms on the clinical outcome of TKIs therapy in Chinese advanced non-small-cell lung cancer patients

Table 3 The association between ABCG2 polymorphisms and clinical characteristics

	34 G/A			P -value	421 C/A			P -value	1143 C/T			P -value
	GG	AG	AA	P -value	CC	CA	AA	P -value	CC	TC	TT	P -value
Gender				0.684				0.501				0.682
Male	19	28	6		31	20	2		34	17	2
Female	17	22	8		22	23	2		32	12	3
Age				0.725				0.167				0.517
≤64	18	29	7		28	22	4		34	18	2
>64	18	21	7		25	21	0		32	11	3
Smoking history				0.564				0.667				0.527
Never	23	32	11		34	30	2		45	17	4
Ever	13	18	3		19	13	2		21	12	1
Histology				0.955				0.816				0.535
Adenocacino	29	41	11		42	36	3		53	23	5
Others	7	9	3		11	7	1		13	6	0
EGFR mutation				0.204				0.119				0.305
Positive	7	14	0		9	10	2		15	6	0
Negative	3	6	2		9	2	0		6	4	1

ISSN: 1475-2867