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Figure 5 | Cancer Cell International

Figure 5

From: MicroRNA-378-5p suppresses cell proliferation and induces apoptosis in colorectal cancer cells by targeting BRAF

Figure 5

Knockdown of BRAF significantly inhibits cell proliferation and induces apoptosis in CRC cells. (A) Down-regulation of BRAF by miR-378-5p mimics and knockdown of BRAF by siRNA significantly inhibited RAS/RAF/MEK/ERK pathway in CRC cells. (B) Knockdown of BRAF by siRNA significantly inhibited proliferation in CRC cells. (C) Knockdown of BRAF by siRNA significantly induced apoptosis in CRC cells. **p <0.01. NC, negative control.

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Cancer Cell International

ISSN: 1475-2867

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