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Table 1 Relationship between B7-H3 expression and clinico-pathological parameters in HCC

From: B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway

Index

Case

B7-H3 expression

 

Low

High

p

Age (y)

    

≤50

43

9

34

0.570

>50

73

15

58

 

Gender

    

Male

84

16

68

0.320

Female

32

8

24

 

Vascular Invasion

    

+

50

3

47

0.001

-

66

21

45

 

TNM stage

    

I-II

20

57

77

0.038

III-IV

4

35

39

 

Lymph metastasis

    

+

32

3

29

0.041

-

84

21

63

 

Tumor size (cm)

    

≤5

77

21

56

0.010

>5

39

3

36

 

Tumor encapsulation

    

+

18

1

17

0.071

-

98

23

75

 

Microsatellite tumors

    

Yes

31

2

29

0.016

No

85

22

63

 

Child-Pugh classification

    

A

60

13

47

0.485

B

56

11

45

 

Liver cirrhosis

    

weak

24

8

16

0.203

moderate

58

10

48

 

strong

34

6

28

 

HBsAg

    

+

76

13

63

0.142

-

40

11

29

 

AFP

    

≤200

48

8

40

0.242

>200

67

16

51

 

Transfusion

    

+

47

8

39

0.286

-

69

16

53

 
  1. Values in bold signify p < 0.05.