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Figure 6 | Cancer Cell International

Figure 6

From: Analyzing the gene expression profile of anaplastic histology Wilms’ tumor with real-time polymerase chain reaction arrays

Figure 6

Ingenuity Pathways Analysis summary. (A) A list of the top two networks with their respective scores obtained from the Ingenuity Pathway Analysis (IPA). (B) A list of molecular and cellular functions with their respective scores obtained from the IPA. (C) Upstream regulator list that includes TP53 and TGFβ1. IPA analysis showed in pediatric anaplastic histology Wilms’ tumor the important upstream regulators are TP53 and TGFβ1 signaling. (D) Most highly rated network in the IPA analysis. The genes that are shaded were determined to be significant based on statistical analysis. The solid line represents a direct interaction between the two gene products and the dotted line indicates an indirect interaction.

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