Table 1 IC 50 mean values for different drugs tested in monolayer and MTS of lung cancer cell lines
Drug | INER-37 2D (μM). | INER-37 MTS (μM). | t- student | INER-51 2D (μM). | INER-51 MTS (μM). | t -student |
|---|---|---|---|---|---|---|
Etoposide | 17.9 | >500 | 0.0001 | 9.9 | >500 | <0.0001 |
Teniposide | 9.5 | >500 | 0.0003 | 3.9 | >500 | <0.0001 |
Doxorubicin | 3.9 | >100 | <0.0001 | 7.9 | 87.3 | 0.014 |
Camptothecin | 9.1 | >100 | 0.004 | 0.01 | >100 | <0.0001 |
5-Fluorouracil | 300 | >500 | NS | 5.0 | >500 | <0.0001 |
Methotrexate | 300 | >500 | NS | 2.6 | >500 | <0.0001 |
Cytosine-Arabinoside | 300 | >500 | NS | 0.95 | >500 | <0.0001 |
Cisplatin | 29.0 | 74.8 | 0,033 | 74.8 | 25.5 | 0,003 |