From: Up regulation of Bax and down regulation of Bcl2 during 3-NC mediated apoptosis in human cancer cells
IC50a (nM)
Compound
HepG2
T47D
HCT116
3-BC
60 ± 3.0
65 ± 2.0
50 ± 3.0
3-NC
55 ± 2.0b
60 ± 3.0b
50 ± 2.0 b
3-TFC
80 ± 4.0
75 ± 4.0
75 ± 2.0
4, 5 MC
140 ± 3.0
160 ± 5.0
120 ± 4.0