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Table 2 Inhibition of cell proliferation by 4-aryl-4H-chromenes

From: Up regulation of Bax and down regulation of Bcl2 during 3-NC mediated apoptosis in human cancer cells

  

IC50a (nM)

 

Compound

HepG2

T47D

HCT116

3-BC

60 ± 3.0

65 ± 2.0

50 ± 3.0

3-NC

55 ± 2.0b

60 ± 3.0b

50 ± 2.0 b

3-TFC

80 ± 4.0

75 ± 4.0

75 ± 2.0

4, 5 MC

140 ± 3.0

160 ± 5.0

120 ± 4.0

  1. aData are means of three or more experiments and are reported as means ± standard error of the mean (SEM)
  2. bData from Ref. [21]