Fig. 2

Effect of silenced miR-545 on radiosensitivity of tumor and Ku70 miRNA expression. Before injected into C57BL/6 mice, the Lewis lung cancer cells were transfected with miR-545 inhibitor. Tumors were irradiated with a single dose of 12 Gy/1f/1d as in Fig. 1. (a) Growth of tumor in irradiated mice. (b) Expression of Ku70 was determined by using quantity RT-PCR in tumors. The results were represented as mean ± SD. ^* P < 0.05 compared with negative control