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Fig. 4 | Cancer Cell International

Fig. 4

From: RB mutation and RAS overexpression induce resistance to NK cell-mediated cytotoxicity in glioma cells

Fig. 4

Ras overexpression and Rb deletion in vivo produce tumours in a syngeneic model. 1x106 cRbloxP/loxP, RasV12, cRb−/−, or cRb−/−/RasV12 transformed astrocytes were subcutaneously injected in FVB immunocompetent mice. Tumours were measured weekly and their volumes (in cubic millimeters) were reported in the graph during 28 days post-implant. Results show the media +/− S.D. of 10 mice

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