Table 1 Relationship between miR-203 expression and clinicopathological features in HCC

Tissue

Adjacent non-cancerous liver

95

2.2408 ± 0.75351

10.170

<0.001

HCC

95

1.1651 ± 0.70378

Age

<50

49

1.0951 ± 0.72640

1.000

0.320

≥50

46

1.2396 ± 0.67884

Gender

male

75

1.1163 ± 0.70032

−1.313

0.192

female

20

1.3480 ± 0.70405

Differentiation

well

6

1.1717 ± 0.53229

0.804^a

0.451

moderate

60

1.2305 ± 0.73598

poor

29

1.0283 ± 0.66507

Size

<5 cm

18

0.9061 ± 0.50149

−2.208

0.034

≥5 cm

77

1.2256 ± 0.73265

Tumor nodes

single

52

1.2960 ± 0.76903

2.026

0.046

multiple

43

1.0067 ± 0.58613

Metastasis

-

46

1.3363 ± 0.77316

2.353

0.021

+

49

1.0043 ± 0.59589

Clinical TNM stage

I-II

22

1.5600 ± 0.79292

3.141

0.002

III-IV

73

1.0460 ± 0.63345

Portal vein tumor embolus

-

63

1.2387 ± 0.76142

1.440

0.153

+

32

1.0200 ± 0.55646

Vaso-invasion

-

59

1.1810 ± 0.76883

0.282

0.779

+

36

1.1389 ± 0.59126

Tumor capsular infiltration

With complete capsule

45

1.1549 ± 0.75314

−0.133

0.895

Infiltration or no capsule

50

1.1742 ± 0.66383

HCV

-

63

1.1073 ± 0.71115

−1.124

0.264

+

32

1.2788 ± 0.68580

HBV

-

17

1.2624 ± 0.51125

0.627

0.532

+

78

1.1438 ± 0.74014

AFP

-

41

1.1173 ± 0.69725

−0.629

0.531

+

38

1.2184 ± 0.73104

Cirrhosis

-

50

1.4912 ± 0.72123

5.436

0.000

+

45

0.8027 ± 0.47296

MTDH

-

38

1.1561 ± 0.69533

0.162

0.872

+

51

1.1320 ± 0.69657

nm23

-

20

1.5965 ± 0.82139

3.237

0.002

+

75

1.0500 ± 0.62628

p53

-

40

1.1412 ± 0.69109

−0.280

0.780

+

55

1.1824 ± .71871

p21

-

62

1.2758 ± 0.72648

2.142

0.035

+

33

0.9570 ± 0.61683

VEGF

-

25

1.4252 ± 0.82009

2.196

0.031

+

70

1.0721 ± 0.63841

Ki-67 LI

Low

47

1.1726 ± 0.76271

0.102

0.919

High

48

1.1577 ± 0.64897

MVD

Low

47

1.1900 ± 0.69824

0.340

0.734

High

48

1.1406 ± 0.71570