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Table 3 Univariate and Multivariate Analysis of Different Prognostic Features in 144 Patients with prostate cancer

From: Increased expression of Six1 correlates with progression and prognosis of prostate cancer

  

Univariate analysisa

 

Multivariate analysisb

Variable

All case

Mean (months)

χ 2

P value

HR (95 % CI)

P value

Agec

  

6.487

0.011

2.220 (1.146–4.300)

0.018

 ≤65

68

111.567

    

 >65

76

96.475

    

Histological grade

  

4.312

0.038

0.696 (0.335–1.446)

0.331

 G1 + G2

77

106.956

    

 G3

67

99.493

    

Clinical stage

  

9.381

0.002

1.369 (0.312–6.004)

0.677

 I + II

40

114.868

    

 III + IV

104

99.086

    

Gleason score

  

9.273

0.002

1.246 (0.391–3.969)

0.710

 1–7

54

111.779

    

 8–10

90

98.610

    

pT status

  

9.381

0.002

1.369 (0.312–6.004)

0.677

 T1 + T2

40

114.868

    

 T3 + T4

104

99.086

    

pN status

  

13.772

0.000

1.710 (0.803–3.642)

0.164

 N0

107

107.933

    

 N1 + N2

37

90.843

    

pM status

  

1.529

0.216

1.162 (0.554–2.437)

0.692

 M0

107

104.893

    

 M1

37

100.275

    

Six1 expression

  

16.051

0.000

3.434 (1.168–10.100)

0.025

 Low

64

113.943

    

 High

80

94.992

    
  1. HR indicates hazards ratio; CI indicates confidence interval
  2. aLog-rank test; bCox regression model; cMean age
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Cancer Cell International

ISSN: 1475-2867

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