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Fig. 6 | Cancer Cell International

Fig. 6

From: MicroRNA-24 inhibits growth, induces apoptosis, and reverses radioresistance in laryngeal squamous cell carcinoma by targeting X-linked inhibitor of apoptosis protein

Fig. 6

Effect of XIAP knockdown on LSCC radiosensitivity. a Radiosensitization by expression of XIAP was based on clonogenic cell survival assays. Stably transfected Hep-2 and AMC-HN-8 were exposed to various doses of radiation prior to plating for clonogenic cell survival. b Flow cytometry of apoptosis in stably transfected Hep-2 and AMC-HN-8 with (6.0Gy) or without irradiation. c Western blot of c-caspase-3, total caspase-3, cleaved c-PARP, and total PARP in stably transfected Hep-2 and AMC-HN-8 with or without irradiation (6.0Gy). GAPDH was used as an internal control. Each experiment was performed at least in triplicate. *P < 0.05, **P < 0.01 vs control

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Cancer Cell International

ISSN: 1475-2867

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