From: AXIN2 rs2240308 polymorphism contributes to increased cancer risk: evidence based on a meta-analysis
Criteria | Score |
---|---|
Representativeness of cases | |
Selected from population or cancer registry | 3 |
Selected from hospital | 2 |
Selected from pathology archives but without description | 1 |
Not described | 0 |
Representativeness of controls | |
Population-based | 3 |
Blood donors or volunteers | 2 |
Hospital-based(cancer-free patients) | 1 |
Not described | 0 |
Specimens of cases determining genotypes | |
White blood cells or normal tissues | 3 |
Tumor tissues or exfoliated cells of tissue | 0 |
Hardy-Weinberg equilibrium in controls | |
Hardy-Weinberg equilibrium | 3 |
Hardy-Weinberg disequilibrium | 0 |
Total sample size | |
≥1000 | 3 |
≥500 but <1000 | 2 |
≥200 but <500 | 1 |
<200 | 0 |