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Table 1 Scale for quality assessment

From: AXIN2 rs2240308 polymorphism contributes to increased cancer risk: evidence based on a meta-analysis

Criteria

Score

Representativeness of cases

 

 Selected from population or cancer registry

3

 Selected from hospital

2

 Selected from pathology archives but without description

1

 Not described

0

Representativeness of controls

 

 Population-based

3

 Blood donors or volunteers

2

 Hospital-based(cancer-free patients)

1

 Not described

0

Specimens of cases determining genotypes

 

 White blood cells or normal tissues

3

 Tumor tissues or exfoliated cells of tissue

0

Hardy-Weinberg equilibrium in controls

 

 Hardy-Weinberg equilibrium

3

 Hardy-Weinberg disequilibrium

0

Total sample size

 

 ≥1000

3

 ≥500 but <1000

2

 ≥200 but <500

1

 <200

0