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Table 1 Shows the pharmacological modulators of P-gp

From: Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

Inducers Inhibitor
Prazosin, Topotecan, Amprena [222], Rifampin, Phenobarbital, Clotrimazole, Reserpine, Isosafrole, Midazolam and Nifedipine [139, 223], Dexamethasone [224]
Morphine [225], Retinoic acid [226], St John’s wort [227]
Carvedilol [228], Cyclosporine [229], Itraconazole [230], Ketoconazole [231],
Synthetic opiates e.g. Meperidine, Methadone, Pentazocine [232], Tamoxifen [233, 234], Vandetanib [235], β-elemene [236]