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Fig. 2 | Cancer Cell International

Fig. 2

From: Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cells

Fig. 2

PA induces cell cycle arrest and apoptosis in human lung cancer cells. a NCI-H23 and NCI-H460 cells were treated with PA (20, 40 or 80 µM) for 24 h, and the number of cells in G2/M phase was determined via flow cytometry. b, c NCI-H23 and NCI-H460 cells were treated with PA (20, 40 or 80 µM) for 24 h, and the cell apoptosis was determined by Annexin V-FITC/PI staining (b) and DNA ladder formation assay (c). Data are presented as mean ± SD from three independent experiments. **P < 0.01 compared with the control group.

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