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Fig. 3 | Cancer Cell International

Fig. 3

From: MicroRNA-125b promotes tumor metastasis through targeting tumor protein 53-induced nuclear protein 1 in patients with non-small-cell lung cancer

Fig. 3

Down-regulation of miR-125b reduced NSCLC metastasis. a NSCLC cells from different patients were transfected with miR-125b inhibitors for 12 h and then assayed for their expression of miR-125b. Each dot represented the results from one patient. b, c NSCLC cells from different patients were transfected with miR-125b inhibitors or the control, respectively, and then assayed for their adhesion activity (n = 4) and invasion (n = 5). d Nude mice were challenged LPS and NSCLC cells that were transfected with miR-125b inhibitors or the control. Lung tumor burden was detected by analyzing lung weight. Data were presented as means (±SD) from five nude mice in each group

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