Skip to main content

Table 1 Associations between miR-645 and clinical parameters (n = 62)

From: Dysregulated miR-645 affects the proliferation and invasion of head and neck cancer cell

Characteristic

No. of patients

miR-645 ∆Cta

P

No.

%

Mean ± SD

Age, years

 ≥60

26

41.9

0.29 ± 0.08

0.173

 <60

36

58.1

0.48 ± 0.11

Sex

 Male

43

69.4

0.37 ± 0.09

0.625

 Female

19

30.6

0.45 ± 0.13

Pathologe grade

 I

26

42.6

0.22 ± 0.076

0.025

 II

27

44.3

0.46 ± 0.12

 III

8

13.1

0.82 ± 0.21

T stage

 T1, 2

27

43.5

0.34 ± 0.08

0.406

 T3, 4

34

54.8

0.46 ± 0.11

N stage

 pN−

28

45.2

0.22 ± 0.05

0.017

 pN+

34

54.8

0.54 ± 0.12

Site

 Tongue

25

41.7

0.32 ± 0.11

0.514

 Gingival

12

20.0

0.44 ± 0.18

 Cheek

7

11.7

0.35 ± 0.16

 Floor of mouth

11

18.3

0.34 ± 0.15

 Oropharynx

5

8.3

0.80 ± 0.41

Histologic signs of severity (vascular emboli, perineural invasion, diffuse infiltration)

 None

26

41.9

0.28 ± 0.05

0.024

 Presence

21

33.9

0.60 ± 0.13

Smoking history

 Nonsmoker

28

45.2

0.41 ± 0.09

0.452

 Smoker

30

48.4

0.32 ± 0.07

Alcohol history

 Nondrinker

38

61.3

0.41 ± 0.08

0.339

 Drinker

20

32.3

0.29 ± 0.07

  1. SD standard deviation, T tumor stage, N lymphnode stage
  2. a∆Ct indicates the difference in the cycle number at which a sample’s fluorescent signal passes a given threshold above baseline (Ct) derived from a specific gene compared with that of U6 in tumor tissues