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Fig. 2 | Cancer Cell International

Fig. 2

From: Long-term primary culture of a clear cell ovarian carcinoma reveals an epithelial–mesenchymal cooperative interaction

Fig. 2

a, b Representative hematoxylin-stained, paraffin-embedded sections of the tumor biopsy utilized for isolating carcinoma cells for primary culture. Images depict a tubulopapillary pattern (arrows in b) with hobnail cells (arrowheads in a) and abundant cells with clear cytoplasm (asterisk in a). Positive immunohistochemical staining for HNF1β with hematoxylin counterstaining (c, d) in the biopsy are shown (arrows, tubuli with positive nuclei; arrowheads depicts positive nuclei in hobnail cells). Hematoxylin-stained sections (e, f), and HNF1β expression (g, h) in a xenograft of human SKOV-3 cells developed in immunosuppressed mice (arrowheads clear cells)

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