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Fig. 4 | Cancer Cell International

Fig. 4

From: Celastrol induces cell cycle arrest by MicroRNA-21-mTOR-mediated inhibition p27 protein degradation in gastric cancer

Fig. 4

Celastrol inhibited mTOR activity through miR-21. Western blot showed that celastrol significantly decreased p-mTOR level in BGC-823and MGC-803 cells (a). mTOR and mTORC2 kinase assays revealed that miR-21 mimic reversed the decrease of mTOR (b) and mTORC2 (c) activity. **P < 0.01, indicate significant differences from the respective control groups

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Cancer Cell International

ISSN: 1475-2867

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