Fig. 6From: Celastrol induces cell cycle arrest by MicroRNA-21-mTOR-mediated inhibition p27 protein degradation in gastric cancerCelastrol increased p27 expression through mTOR. Western blot analyses revealed that mTORSL1+IT reversed the increase of p27 protein level in BGC-823 and MGC-803 cells treated with celastrol (a). The real-time PCR revealed that mTORSL1+IT had no effect of p27 mRNA level in BGC-823 and MGC-803 cells treated with celastrol (b)Back to article page