Fig. 5
From: Dimethylsulfoxide excerbates cisplatin-induced cytotoxicity in Ehrlich ascites carcinoma cells
A photomicrograph of a section of rat kidney treated with cisplatin (7.5 mg/kg, i.p.) showing disruption of epithelium of the proximal convoluted tubule (thick black arrow) and distal convoluted tubule (white arrow). Karyorrhetic nuclei within the vacuolated cytoplasm of the tubular epithelium (dashed arrows) are observed. (filled star) Pyknotic nuclei are noticed (thin black arrows) in the endothelial and mesangial cells of the glomerulus (G). Dilated congested blood vessels (bv) and intertubular capillaries are also noticed (H&E ×400)