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Table 4 Effect of treatment with cisplatin and/or DMSO on serum urea and creatinine levels

From: Dimethylsulfoxide excerbates cisplatin-induced cytotoxicity in Ehrlich ascites carcinoma cells

Treated groups

Parameters

Urea (mg/dl)

Creatinine (mg/dl)

Normal saline

48 ± 1.7

0.51 ± 0.02

50 % DMSO

52 ± 0.49

0.54 ± 0.04

Cisplatin

237 ± 11.51a

3 ± 0.25a

Cisplatin and 50 % DMSO

73 ± 3.44a,b

0.73 ± 0.11a,b

  1. Values are expressed in mean ± SEM (n = 5)
  2. aSignificantly different from control at P value <0.05
  3. bSignificantly different from CIS at P value <0.05, one way ANOVA with LSD post test