Gene name | Gene symbol | R2-2 vs. M13SV1 | R2-N1 vs. M13SV1 | ||
---|---|---|---|---|---|
Fold regulation | p-value | Fold regulation | p-value | ||
Androgen receptor | AR | 4.59 | 0.096 | 4.48 | 0.230 |
BCL2-associated agonist of cell death | BAD | −1.20 | 0.723 | 1.26 | 0.675 |
BCL2-associated athanogene | BAG1 | −1.18 | 0.545 | −1.39 | 0.043 |
B-cell CLL/lymphoma 2 | BCL2 | −1.62 | 0.197 | −2.65 | 0.088 |
BCL2-like 2 | BCL2L2 | 1.02 | 0.914 | 1.94 | 0.246 |
Complement component 3 | C3 | 1.17 | 0.733 | 1.14 | 0.890 |
Cyclin A1 | CCNA1 | −2.32 | 0.009 | 1.72 | 0.010 |
Cyclin A2 | CCNA2 | 1.53 | 0.069 | 1.25 | 0.489 |
Cyclin D1 | CCND1 | 1.26 | 0.879 | 1.13 | 0.836 |
Cyclin E1 | CCNE1 | 1.69 | 0.078 | 2.11 | 0.038 |
CD44 molecule (Indian blood group) | CD44 | 1.20 | 0.740 | 1.30 | 0.572 |
Cadherin 1, type 1, E-cadherin (epithelial) | CDH1 | 1.29 | 0.493 | 1.29 | 0.537 |
Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | CDKN1A | −1.84 | 0.004 | 1.39 | 0.190 |
Cyclin-dependent kinase inhibitor 1B (p27, Kip1) | CDKN1B | 1.52 | 0.286 | −1.08 | 0.764 |
Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | CDKN2A | −1.15 | 0.056 | −1.08 | 0.998 |
Claudin 7 | CLDN7 | 1.29 | 0.671 | −1.19 | 0.713 |
Clusterin | CLU | 2.24 | 0.109 | −1.41 | 0.336 |
Collagen, type VI, alpha 1 | COL6A1 | 1.60 | 0.346 | 4.49 | 0.010 |
Catenin (cadherin-associated protein), beta 1, 88 kDa | CTNNB1 | 2.36 | 0.139 | 1.94 | 0.393 |
Cathepsin B | CTSB | −1.05 | 0.817 | 1.46 | 0.155 |
Cathepsin D | CTSD | 1.59 | 0.178 | 1.04 | 0.876 |
Cytochrome P450, family 19, subfamily A, polypeptide 1 | CYP19A1 | 1.06 | 0.836 | 1.91 | 0.154 |
Deleted in liver cancer 1 | DLC1 | 1.37 | 0.564 | −1.48 | 0.370 |
Epidermal growth factor receptor | EGFR | 1.41 | 0.421 | 1.04 | 0.986 |
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | ERBB2 | 2.03 | 0.355 | 8.15 | 0.062 |
Estrogen receptor 1 | ESR1 | 1.59 | 0.217 | −1.60 | 0.256 |
Estrogen receptor 2 (ER beta) | ESR2 | 1.69 | 0.298 | 2.10 | 0.166 |
Fas (TNF receptor superfamily, member 6) | FAS | −1.06 | 0.681 | −1.16 | 0.499 |
Fas ligand (TNF superfamily, member 6) | FASLG | 1.38 | 0.301 | 1.47 | 0.109 |
Fibroblast growth factor 1 (acidic) | FGF1 | 1.14 | 0.801 | 2.94 | 0.084 |
Fibronectin leucine rich transmembrane protein 1 | FLRT1 | 1.13 | 0.483 | 1.83 | 0.196 |
FOS-like antigen 1 | FOSL1 | −1.14 | 0.546 | 1.51 | 0.192 |
Gamma-aminobutyric acid (GABA) A receptor, pi | GABRP | 2.64 | 0.138 | 1.27 | 0.511 |
GATA binding protein 3 | GATA3 | −1.23 | 0.550 | −2.70 | 0.092 |
GNAS complex locus | GNAS | 1.07 | 0.827 | 1.23 | 0.832 |
Gelsolin | GSN | −1.09 | 0.904 | 1.14 | 0.731 |
High mobility group box 1 | HMGB1 | −1.09 | 0.455 | 1.18 | 0.402 |
Heat shock 27 kDa protein 1 | HSPB1 | 1.53 | 0.042 | 1.16 | 0.533 |
Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | ID2 | −1.09 | 0.677 | −1.46 | 0.380 |
Insulin-like growth factor binding protein 2, 36 kDa | IGFBP2 | 1.06 | 0.794 | −3.35 | 0.262 |
Interleukin 2 receptor, alpha | IL2RA | 1.16 | 0.404 | 1.48 | 0.109 |
Interleukin 6 (interferon, beta 2) | IL6 | −1.99 | 0.114 | 1.07 | 0.884 |
Interleukin 6 receptor | IL6R | 1.49 | 0.006 | 1.50 | 0.145 |
Interleukin 6 signal transducer (gp130, oncostatin M receptor) | IL6ST | 1.62 | 0.266 | 1.35 | 0.547 |
Integrin, alpha 6 | ITGA6 | −1.07 | 0.600 | 1.17 | 0.505 |
Integrin, beta 4 | ITGB4 | 1.20 | 0.812 | −1.02 | 0.824 |
Jun proto-oncogene | JUN | 1.05 | 0.997 | 1.02 | 0.686 |
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | KIT | 4.73 | 0.044 | 4.81 | 0.233 |
Kruppel-like factor 5 (intestinal) | KLF5 | −1.37 | 0.301 | −1.29 | 0.399 |
Kallikrein-related peptidase 5 | KLK5 | −1.80 | 0.241 | −1.41 | 0.431 |
Keratin 18 | KRT18 | 1.48 | 0.026 | 1.36 | 0.042 |
Keratin 19 | KRT19 | 2.30 | 0.031 | 1.87 | 0.146 |
Mitogen-activated protein kinase kinase 7 | MAP2K7 | 2.40 | 0.121 | 1.58 | 0.515 |
Antigen identified by monoclonal antibody Ki-67 | MKI67 | 1.48 | 0.029 | 1.19 | 0.362 |
Metallothionein 3 | MT3 | −2.40 | 0.310 | −1.48 | 0.828 |
Mucin 1, cell surface associated | MUC1 | −1.30 | 0.540 | −1.72 | 0.289 |
Nuclear transcription factor Y, beta | NFYB | 1.26 | 0.571 | 1.20 | 0.746 |
Nerve growth factor (beta polypeptide) | NGF | 1.17 | 0.501 | 1.16 | 0.484 |
Nerve growth factor receptor | NGFR | 1.53 | 0.633 | 2.61 | 0.173 |
Non-metastatic cells 1, protein (NM23A) expressed in | NME1 | 1.21 | 0.345 | 1.31 | 0.300 |
Pregnancy-associated plasma protein A, pappalysin 1 | PAPPA | −1.03 | 0.682 | −2.57 | 0.085 |
Progesterone receptor | PGR | −1.06 | 0.684 | −4.92 | 0.163 |
Plasminogen activator, urokinase | PLAU | 1.16 | 0.672 | 1.66 | 0.113 |
Phosphatase and tensin homolog | PTEN | −1.13 | 0.797 | 1.05 | 0.735 |
Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | PTGS2 | −1.90 | 0.157 | −3.64 | 0.104 |
Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | RAC2 | 1.71 | 0.039 | 2.11 | 0.052 |
Ribosomal protein L27 | RPL27 | −1.02 | 0.767 | 1.16 | 0.254 |
Secretoglobin, family 1D, member 2 | SCGB1D2 | 1.12 | 0.697 | 1.29 | 0.439 |
Secretoglobin, family 2A, member 1 | SCGB2A1 | −2.02 | 0.084 | −1.78 | 0.142 |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | SERPINA3 | 10.61 | 0.008 | 16.47 | 0.201 |
Serpin peptidase inhibitor, clade B (ovalbumin), member 5 | SERPINB5 | −1.25 | 0.028 | −1.12 | 0.448 |
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | SERPINE1 | −1.31 | 0.206 | −1.55 | 0.434 |
Solute carrier family 7 (amino acid transporter light chain, L system), member 5 | SLC7A5 | 1.52 | 0.505 | -1.08 | 0.910 |
Small proline-rich protein 1B | SPRR1B | −1.13 | 0.703 | −1.32 | 0.363 |
Stanniocalcin 2 | STC2 | −1.42 | 0.038 | −1.23 | 0.562 |
Trefoil factor 1 | TFF1 | −9.16 | 0.005 | 1.04 | 0.858 |
Transforming growth factor, alpha | TGFA | −1.26 | 0.376 | −1.37 | 0.387 |
Thrombospondin 1 | THBS1 | 1.01 | 0.995 | −1.49 | 0.122 |
Thrombospondin 2 | THBS2 | −1.09 | 0.602 | 5.09 | 0.008 |
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | TIE1 | 1.08 | 0.836 | 2.10 | 0.153 |
Tumor necrosis factor, alpha-induced protein 2 | TNFAIP2 | 1.09 | 0.782 | −1.05 | 0.921 |
Topoisomerase (DNA) II alpha 170 kDa | TOP2A | 1.75 | 0.048 | 1.25 | 0.526 |
Tumor protein p53 | TP53 | 1.19 | 0.690 | 1.14 | 0.786 |
Vascular endothelial growth factor A | VEGFA | 1.09 | 0.588 | −1.12 | 0.785 |