TY - JOUR AU - Bourgeois, Danielle L. AU - Kabarowski, Karl A. AU - Porubsky, Veronica L. AU - Kreeger, Pamela K. PY - 2015 DA - 2015/12/07 TI - High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation JO - Cancer Cell International SP - 112 VL - 15 IS - 1 AB - The factors driving the onset and progression of ovarian cancer are not well understood. Recent reports have identified cell lines that are representative of the genomic pattern of high-grade serous ovarian cancer (HGSOC), in which greater than 90 % of tumors have a mutation in TP53. However, many of these representative cell lines have not been widely used so it is unclear if these cell lines capture the variability that is characteristic of the disease. SN - 1475-2867 UR - https://doi.org/10.1186/s12935-015-0263-4 DO - 10.1186/s12935-015-0263-4 ID - Bourgeois2015 ER -