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Fig. 2 | Cancer Cell International

Fig. 2

From: High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation

Fig. 2

The effects of growth factors on single cell migration of HGSOC cell lines. HGSOC cell lines were seeded in transwells with 10 ng/mL HB-EGF, NRG1β, IGF1, or HGF in the bottom compartment. Following 48 h, cells that had migrated through the transwell were stained with Calcein-AM and the relative fluorescence was measured. For every cell line, an MDA-MB-231 positive control was performed in parallel; fluorescence for these cells was at least fivefold higher than for the HGSOC conditions. Data presented as the average ± SD, n = 3. *p < 0.05 compared to vehicle

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