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Fig. 5 | Cancer Cell International

Fig. 5

From: Targeted tumor therapy by Rubia tinctorum L.: analytical characterization of hydroxyanthraquinones and investigation of their selective cytotoxic, adhesion and migration modulator effects on melanoma cell lines (A2058 and HT168-M1)

Fig. 5

Apoptotic effects of alizarin, purpurin and aqueous extract. Two different melanoma cell lines (A2058 and HT168-M1) and normal fibroblast cells (MRC-5) were applied as model cells and were incubated with the anthraquinones (10−5 M) for 72 h. The ‘Ratio of apoptotic cells’ is expressed as a percentage of viable cells measured by flow cytometry. Data shown in the figure represent mathematical averages of two parallels and ± S.D. values. The level of significance is shown as follows: *p < 0.05

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