|
Compound
|
Conc. [M]
|
Slopea (%) (control = 100 %)
|
|---|
|
A2058
|
HT168-M1
|
MRC-5
|
|---|
|
Alizarin
|
10−8
|
88.9 ± 6.74
|
100.4 ± 3.05
|
99.3 ± 4.96
|
|
10−7
|
100.6 ± 4.01
|
104.3 ± 3.16
|
104.7 ± 0.82
|
|
10−6
|
110.8 ± 6.38
|
110.4 ± 1.37
|
100.2 ± 2.44
|
|
10−5
|
90.4 ± 8.7
|
107.3 ± 6.51
|
95.5 ± 7.08
|
|
Purpurin
|
10−8
|
85.6 ± 4.36
|
93.6 ± 4.91
|
102.1 ± 5.44
|
|
10−7
|
97.6 ± 1.86
|
101.0 ± 3.42
|
103.7 ± 2.22
|
|
10−6
|
95.2 ± 14.01
|
97.8 ± 15.16
|
109.6 ± 2.4
|
|
10−5
|
115.6 ± 6.56
|
110.2 ± 4.03
|
93.8 ± 5.14
|
|
Aqueous extract
|
10−8
|
99.3 ± 4.96
|
102.1 ± 5.44
|
105.4 ± 1.64
|
|
10−7
|
104.7 ± 0.82
|
103.7 ± 2.22
|
104.5 ± 1.99
|
|
10−6
|
100.2 ± 2.44
|
109.6 ± 2.4
|
98.4 ± 4.25
|
|
10−5
|
95.5 ± 7.08
|
93.8 ± 5.14
|
91.7* ± 2.58
|
- Two different melanoma cell lines (HT168-M1) and normal fibroblast cells (MRC-5) were applied as model cells
- Data shown in the table represent mathematical averages of three parallels and ± S.D. values
- The level of significance is shown as follows: * p < 0.05
-
aThe slope values are expressed in percentage of the control and describe the changing rate of Delta CI in first 3 h’ time interval of cell adhesion
