Table 2 Correlation between DIXDC1 expression and clinicopathological parameters in two types of gastric carcinoma
Clinicopathological feature | Intestinal-type gastric carcinoma | Diffuse-type gastric carcinoma | ||||
|---|---|---|---|---|---|---|
DIXDC1 + (n = 97) | DIXDC1 − (n = 54) | P value | DIXDC1 + (n = 13) | DIXDC1 − (n = 66) | P value | |
Gender | 0.786 | 0.886 | ||||
Male | 79 | 43 | 8 | 42 | ||
Female | 18 | 11 | 5 | 24 | ||
Age | 0.018 | 0.072 | ||||
≥60 years | 59 | 22 | 8 | 23 | ||
<60 years | 38 | 32 | 5 | 43 | ||
Size | 0.036 | 0.563 | ||||
≥5 cm | 27 | 7 | 5 | 20 | ||
<5 cm | 70 | 47 | 8 | 46 | ||
Differentiation | 0.003 | – | ||||
High grade | 40 | 36 | 0 | 0 | ||
Low grade | 57 | 18 | 13 | 66 | ||
Depth of invasion | <0.001 | 0.756 | ||||
T1 | 13 | 29 | 3 | 18 | ||
T2 | 18 | 6 | 1 | 9 | ||
T3 + T4 | 66 | 19 | 9 | 39 | ||
Lymph node metastases | <0.001 | 0.506 | ||||
Negative | 30 | 37 | 6 | 24 | ||
Positive | 67 | 17 | 7 | 42 | ||
Clinical stage | 0.003 | 0.650 | ||||
I/II | 56 | 44 | 7 | 40 | ||
III/IV | 41 | 10 | 6 | 26 | ||