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Fig. 5 | Cancer Cell International

Fig. 5

From: Cytotoxic and apoptogenic effect of hypericin, the bioactive component of Hypericum perforatum on the MCF-7 human breast cancer cell line

Fig. 5

ICC staining of p53 in MCF-7 cells. ICC staining of p53 in untreated MCF-7 cells (a) (utilizing DAPI nuclear dye, stains cells nuclei blue [middle columns]). ICC results for p53 in the cells after treatment of cells with 20 (μg/ml) of cisplatin after 24 h (b), 7.5 (μg/ml) cisplatin after 48 h (c), 5 (μg/ml) of hypercin after 24 h (d), 0.5 (μg/ml) hypercin after 48 h (e). More cells are stained green (for p53) after treatment cisplatin and/or hypercin. (original magnification ×400; scale bar 50 µm)

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