Table 1 Summary of cell cycle arrest patterns in two lung cancer cells induced by 2-DG
From: Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth
Exposure time (h) | Treatment | Cell lines | |||||||
|---|---|---|---|---|---|---|---|---|---|
KP2 | H23 | ||||||||
G1% | %G2 | S% | %Sub G1 | G1% | %G2 | S% | %Sub G1 | ||
12 | Control | 21.86 | 3.61 | 74.53 | 0.5 | 32.71 | 38.81 | 28.47 | 2.79 |
12 | 2-DG | 44.40 | 0.96 | 54.64 | 0.71 | 31.56 | 48.78 | 19.65 | 3.47 |
36 | Control | 20.96 | 2.01 | 77.05 | 0.54 | 29.53 | 40.66 | 29.80 | 2.76 |
36 | 2-DG | 70.48 | 0.77 | 28.75 | 2.22 | 34.26 | 48.83 | 16.92 | 4.04 |
60 | Control | 29.03 | 0.00 | 70.97 | 0.45 | 31.41 | 38.88 | 29.71 | 2.54 |
60 | 2-DG | 87.37 | 7.67 | 4.95 | 4.23 | 39.84 | 43.58 | 16.59 | 8.85 |