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Fig. 1 | Cancer Cell International

Fig. 1

From: Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells

Fig. 1

Melatonin promotes apoptosis of SGC-7901 gastric cancer cells. SGC-7901 cells were incubated with melatonin for the indicated doses and periods. a The morphological figures of apoptosis were monitored by fluorescence microscopy after staining with Hoechst 33258. Images are representative of at least three independent determinations. Scale bar 50 μm. b Melatonin-induced apoptosis of SGC-7901 gastric cancer cells. Values were presented as mean ± SD of three independent experiments. c Cell proliferation was measured by MTT assay. d Apoptosis was evaluated for up to 48 h by Hoechst 33258 staining. Images are representative of at least three independent determinations. Scale bar 50 μm. **P < 0.01

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