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Fig. 5 | Cancer Cell International

Fig. 5

From: Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells

Fig. 5

Effects of SB203580, LY294002 and HSP27 silencing on melatonin-induced cell apoptosis. a Effects of SB203580, LY294002 and siHSP27 on melatonin stimulated cell apoptosis and necrosis were measured with FACS assay. *P < 0.05, **P < 0.01. b, c After incubation with melatonin for 24 h, total protein extracts from SGC-7901 cells transfected with HSP27 siRNA or control siRNA were analyzed by immunoblotting for P-Akt (b) and P-P38 (c). *P < 0.05

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