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Table 3 The combination index values at different effect levels for the combination of fisetin and paclitaxel

From: Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells

Fa 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9
CI 0.17 0.09 0.09 0.12 0.16 0.22 0.34 0.57 1.27
  1. The CI values were calculated according to the method of Chou–Talalay using CompuSyn software. CI < 1 represents synergism, with a CI of 0.1–0.3 indicating strong synergism, 0.3–0.7 indicating synergism, and CI of 0.7–0.85 indicating moderate synergism