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Fig. 4 | Cancer Cell International

Fig. 4

From: Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative

Fig. 4

Thieno[2,3-b] induce multinucleated phenotype but not microtubules bundle formation. The effect of paclitaxel and derivative 3 on MDA-MB-231 breast cancer cells with microtubule filaments stained with FITC-labelled anti-tubulin antibody (green fluorescence). DNA in the nucleus was stained with Hoechst staining (blue fluorescence). Cells were treated with or without drugs for 16 h. Multi-nucleated cells were observed by derivative 3 treatment. The arrow indicates membrane blebbing

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Cancer Cell International

ISSN: 1475-2867

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