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Fig. 6 | Cancer Cell International

Fig. 6

From: Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative

Fig. 6

Synergy using thieno[2,3-b]pyridine with cytotoxic drugs. The growth inhibitory effects of derivative 3 (50 nM) in combination with cytotoxic drugs on breast cancer cell line MDA-MB-231 and the colon breast cancer cell line HCT116. An average of two independent experiments is shown. CPT camptothecin, DOX doxorubicin, TAXOL paclitaxel; and PLC, derivative 3. The dashed line represents the theoretical expectation when the combined effects of chemicals are additive (Bliss curve)

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Cancer Cell International

ISSN: 1475-2867

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