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Table 1 The results of the pharmacokinetic study

From: Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative

Parameter

Value

Ke,1/h

0.017

t1/2, h

4.11

Cmax, µmol/L

0.087

AUC0–6 h, µmol/L × h

0.13

AUC0–∞, µmol/L × h

0.19

  1. K e elimination rate constant, t 1/2 elimination half-life, C max maximum concentration in plasma, AUC area under the plasma concentration–time curve up to 6 h and extrapolated to infinity