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Fig. 6 | Cancer Cell International

Fig. 6

From: MiR-519d facilitates the progression and metastasis of cervical cancer through direct targeting Smad7

Fig. 6

Depletion of Smad7 restored the migration and invasion of cervical cancer cells under miR-519d inhibition. a Transwell assay was performed to determine the migration capacity of HeLa and SiHa cells after transfection of miR-519d inhibitor and Smad7 shRNA independently or simultaneously compared with NC group. b, c Statistical analysis of the number of migrated cells in the indicated groups (*P < 0.05). d Matrigel transwell assay was performed to determine the invasion capacity of HeLa and SiHa cells after transfection of miR-519d inhibitor and Smad7 shRNA independently or simultaneously compared with NC group. e, f Quantitative analysis of the number of cells invading through matrigel in the indicated groups (*P < 0.05)

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