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Fig. 4 | Cancer Cell International

Fig. 4

From: Basigin-2 upregulated by receptor activator of NF-κB ligand enhances lung cancer-induced osteolytic lesions

Fig. 4

The promotion effect of basigin-2 on the osteolytic lesions. a The X-rays of the hind limb of mice injected with A549, basigin-2/A549 or shbasigin-2/A549 cells compared with normal mouse. b Evaluation of the incidence of tumor take (left two panel) and bone densitometric analysis of the radiographs assessing the osteolytic areas taken at the end point of the experiment (right panel). Inset numbers, number of tibia developing osteolytic lesions mice/number of tibia injected mice. *P < 0.05, by Student’s t test. c The X-rays of the tibia of mice injected with basigin-2/A549 cells treated using basigin-2 blocking antibody compared with IgG control. d Evaluation of the incidence of tumor take (left two panel) and bone densitometric analysis of the radiographs assessing the osteolytic areas taken at the end point of the experiment (right panel). Inset numbers, number of tibia developing osteolytic lesions mice/number of tibia injected mice. *P < 0.05, by Student’s t test

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Cancer Cell International

ISSN: 1475-2867

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