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Fig. 3 | Cancer Cell International

Fig. 3

From: The BH3 mimetic drug ABT-737 induces apoptosis and acts synergistically with chemotherapeutic drugs in thyroid carcinoma cells

Fig. 3

Increases in apoptosis markers and LDH release after treatment with 1 µM ABT-737 for 24 h. Caspase 3 and 7 activities (a) were determined by the ApoOne assay, cleaved caspase 3 (b) and cleaved PARP (c) concentrations were determined by specific ELISAs, and values for LDH-release into the medium (d) were determined by CytoTox-assay. All values are depicted as percent of vehicle-treated control, mean ± standard deviation from eightfold determinations; *indicates significant increase (p < 0.05, Student’s t test)

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