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Fig. 3 | Cancer Cell International

Fig. 3

From: Induction of G1-phase cell cycle arrest and apoptosis pathway in MDA-MB-231 human breast cancer cells by sulfated polysaccharide extracted from Laurencia papillosa

Fig. 3

Expression analysis of cyclin/Cdks and Cdks inhibitory (Ckis) genes in ASPE-treated MDA-MB-231 cells. Cells were exposed to 10 and 30 µg/mL of ASPE for 24 h. Change in gene expression in MDA-MB-231 cells of tested genes is mentioned in diagrams as fold change (ratio of target/reference gene). The results were divided in three groups: cyclin gene, cyclin-dependent kinase genes (Cdks) and cyclin-dependent kinase inhibitory genes (Ckis). Each data point represents the mean (±SEM) of three independent experiments. Asterisks indicate significant difference (P < 0.05)

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