Fig. 4

Nodal mostly co-localizes to Rab7 and Rab11 in more differentiated GBM cells. Pearson’s coefficient of relative amount of co-localization of endosomal markers/Nodal in OB1 and differentiated OB1 cell cultures (quantification of average across three separate fields, each containing an average of three to four spheroids—OB1 cells—or 20–30 cells—differentiated OB1 cells). Data means are ± SD. ***P < 0.001 by two-way ANOVA for repeated measures followed by Tukey’s test for correction of the P value