Fig. 1
From: MiR-145 functions as a tumor suppressor via regulating angiopoietin-2 in pancreatic cancer cells
Down-regulation of miR-145 accompanied with up-regulation of Ang-2 in more aggressive pancreatic cancer cells. a, b The invasion ability of BxPC3, MiaPaca-2 and Panc-1 cells was measured by in vitro invasion assay; c the expression level of miR-145 in BxPC3, MiaPaca-2 and Panc-1 cells was measured by qRT-PCR; d the expression levels of Ang-2 mRNA and protein in BxPC3, MiaPaca-2 and Panc-1 cells were measured by qRT-PCR and western blotting, respectively. Data represents the mean ± SEM, n = 3, significant differences compared to BxPC3 group are indicated as *P < 0.05, **P < 0.01, ***P < 0.001 (one-way ANOVA followed by Bonferroni test)