Expression and diagnostic value of CCT3 and IQGAP3 in hepatocellular carcinoma

Table 1 Clinical characteristics of patients with HCC

Parameters	Patients, n (%)	CCT3	P value	IQGAP3	P value
Parameters	Patients, n (%)	\(\overline{\text{x}}\) ± SD, pg/mL	P value	\(\overline{\text{x}}\) ± SD, pg/mL	P value
Age (years)
≤55	38 (30.2)	285.53 ± 203.38	0.106^a	217.79 ± 163.06	0.043^a
>55	88 (69.8)	350.6 ± 207.33	0.106^a	287.83 ± 181.55	0.043^a
Gender
Male	84 (66.7)	354.67 ± 217.39	0.08^a	270.35 ± 167.19	0.748^a
Female	42 (33.3)	283.6 ± 199.51	0.08^a	259.43 ± 201.11	0.748^a
Etiology
HBV(+)	72 (57.1)	284.79 ± 195.82	0.019^b	218.82 ± 177.52	0.002^b
HCV(+)	31 (24.6)	407.16 ± 209.483		342.32 ± 150.01
Other	23 (18.3)	72.87 ± 209.96		314.70 ± 74.99
Tumor diameter (cm)
≤2	47 (37.3)	279.13 ± 217.01	0.011^b	212.74 ± 170.72	0.025^b
>2 and ≤5	25 (19.8)	432.92 ± 155.60		327.80 ± 138.07
>5	54 (42.9)	328.91 ± 205.99		285.39 ± 191.04
Number of lesions
≤2	61 (48.4)	272.52 ± 200.87	0.002^a	230.36 ± 166.22	0.026^a
>2	65 (51.6)	385.83 ± 199.91	0.002^a	300.82 ± 184.04	0.026^a
Extra-hepatic metastasis
Yes	34 (27.0)	407.00 ± 215.60	0.014^a	334.03 ± 207.84	0.27^a
No	92 (73.0)	302.88 ± 198.33	0.014^a	241.83 ± 160.53	0.27^a
Differentiation degree
Well	47 (37.3)	316.21 ± 208.54	0.245^b	252.85 ± 154.02	0.133^b
Moderate	43 (34.1)	308.37 ± 201.41		235.53 ± 178.15
Poor	36 (28.6)	377.25 ± 211.73		322.03 ± 199.74
TNM stage
I + II	71 (56.3)	282.56 ± 199.01	0.003^a	232.5 ± 158.43	0.017^a
III + IV	55 (43.7)	393.47 ± 203.17	0.003^a	310.85 ± 194.09	0.017^a
Child-pugh classification
A	51 (40.4)	265.75 ± 209.34	0.006^b	203.08 ± 164.94	0.000^b
B	33 (26.3)	400.58 ± 199.30		357.45 ± 149.83
C	42 (33.3)	355.50 ± 192.4		272.67 ± 186.31

HBV hepatics B virus, HCV hepatics C virus, HCC hepatocellular carcinoma, SD standard deviation, TNM tumor-node-metastasis
^aBy Mann–Whitney U test
^bBy Kruskal–Wallis test

ISSN: 1475-2867