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Table 4 Multivariate analysis of Cox proportional hazards model of 5-year OS and PFS for the patients of the IC + CCRT group (n = 134)

From: Positive effect of HPV status on prognostic value of blood lymphocyte-to-monocyte ratio in advanced cervical carcinoma

Prognostic factors

OS

PFS

Hazard ratio

95 % CI

p value

Hazard ratio

95 % CI

p value

LMR: high versus low

0.362

0.181–0.523

0.010

0.329

0.325–0.693

0.018

HPV DNA status: HR-positive HPV DNA versus non-HR HPV DNA

0.203

0.025–0. 425

0.001

0.317

0.104–0.672

0.028

Age: ≤46 versus >46

0.532

0.121–0.727

0.063

1.021

0.876–3.672

0.153

FIGO classification: IIA versus IIB versus IIIA versus IIIB versus IIIB versus IVA

0.186

0.087–0.439

0.035

0.238

0.0137–0.639

0.033

pathological type: SCC versus ADC versus ASC versus UDC

0.416

0.087–0.539

0.010

0.286

0.187–0.441

0.011

Lymph node status classification: positive lymph node versus negative lymph node

1.475

0.987–3.439

0.043

2.753

1.587–4.339

0.045

ALC: high versus low

0.460

0.108–0.732

0.030

0.421

0.265–0.828

0.001

AMC: high versus low

1.814

1.049–3.738

0.131

0.682

0.212–1.225

0.135

  1. OS overall survival; PFS progression-free survival; CI confidence interval; LMR lymphocyte-to-monocyte ratio; HPV human papillomavirus; DNA deoxyribonucleic acid; HR high risk; FIGO International Federation of Gynecology and Obstetrics; SCC squamous cell carcinoma; ADC adenocarcinoma; ASC adenosquamous carcinoma; UDC undifferentiated carcinoma; IC inductive chemotherapy; CCRT concurrent chemoradiotherapy; RT radiation therapy; AMC absolute monocyte count; ALC absolute lymphocyte count