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Table 6 Multivariate analysis of Cox proportional hazards model of 5-year OS and PFS for the patients of the IC + RT group (n = 143)

From: Positive effect of HPV status on prognostic value of blood lymphocyte-to-monocyte ratio in advanced cervical carcinoma

Prognostic factors

OS

PFS

Hazard ratio

95 % CI

p value

Hazard ratio

95 % CI

p value

LMR: high versus low

0.471

0.229–0.634

0.010

0.430

0.436–0.794

0.027

HPV DNA status: HR-positive HPV DNA versus non-HR HPV DNA

0.314

0.036–0.536

0.012

0.418

0.215–0.738

0.039

Age: ≤46 versus >46

0.643

0.232–0.837

0.074

1.132

0.987–3.783

0.264

FIGO classification: IIA versus IIB versus IIIA versus IIIB versus IIIB versus IVA

0.297

0.198–0.540

0.045

0.395

0.0245–0.740

0.044

pathological type: SCC versus ADC versus ASC versus UDC

0.527

0.186–0.640

0.036

0.397

0.298–0.552

0.023

Lymph node status classification: positive lymph node versus negative lymph node

2.586

0.987–4.540

0.073

2.753

1.747–5.394

0.065

ALC: high versus low

0.548

0.098–0.931

0.012

0.589

0.065–0.938

0.015

AMC: high versus low

0.829

0.152–1.730

0.321

0.771

0.413–2.313

0.421

  1. OS overall survival; PFS progression-free survival; CI confidence interval; LMR lymphocyte-to-monocyte ratio; HPV human papillomavirus; DNA deoxyribonucleic acid; HR high risk; FIGO International Federation of Gynecology and Obstetrics; SCC squamous cell carcinoma; ADC adenocarcinoma; ASC adenosquamous carcinoma; UDC undifferentiated carcinoma; IC inductive chemotherapy; CCRT concurrent chemoradiotherapy; RT radiation therapy; AMC absolute monocyte count; ALC absolute lymphocyte count