TY - JOUR AU - Margueron, R. AU - Reinberg, D. PY - 2011 DA - 2011// TI - The polycomb complex PRC2 and its mark in life JO - Nature VL - 469 UR - https://doi.org/10.1038/nature09784 DO - 10.1038/nature09784 ID - Margueron2011 ER - TY - JOUR AU - Lawlor, E. R. AU - Thiele, C. J. PY - 2012 DA - 2012// TI - Epigenetic changes in pediatric solid tumors: promising new targets JO - Clin Cancer Res VL - 18 UR - https://doi.org/10.1158/1078-0432.CCR-11-1921 DO - 10.1158/1078-0432.CCR-11-1921 ID - Lawlor2012 ER - TY - JOUR AU - Varambally, S. AU - Cao, Q. AU - Mani, R. S. AU - Shankar, S. AU - Wang, X. AU - Ateeq, B. PY - 2008 DA - 2008// TI - Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer JO - Science VL - 322 UR - https://doi.org/10.1126/science.1165395 DO - 10.1126/science.1165395 ID - Varambally2008 ER - TY - JOUR AU - Varambally, S. AU - Dhanasekaran, S. M. AU - Zhou, M. AU - Barrette, T. R. AU - Kumar-Sinha, C. AU - Sanda, M. G. PY - 2002 DA - 2002// TI - The polycomb group protein EZH2 is involved in progression of prostate cancer JO - Nature VL - 419 UR - https://doi.org/10.1038/nature01075 DO - 10.1038/nature01075 ID - Varambally2002 ER - TY - JOUR AU - Kleer, C. G. AU - Cao, Q. AU - Varambally, S. AU - Shen, R. AU - Ota, I. AU - Tomlins, S. A. PY - 2003 DA - 2003// TI - EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells JO - Proc Natl Acad Sci USA VL - 100 UR - https://doi.org/10.1073/pnas.1933744100 DO - 10.1073/pnas.1933744100 ID - Kleer2003 ER - TY - JOUR AU - Wagener, N. AU - Macher-Goeppinger, S. AU - Pritsch, M. AU - Hüsing, J. AU - Hoppe-Seyler, K. AU - Schirmacher, P. PY - 2010 DA - 2010// TI - Enhancer of zestehomolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma JO - BMC Cancer VL - 10 UR - https://doi.org/10.1186/1471-2407-10-524 DO - 10.1186/1471-2407-10-524 ID - Wagener2010 ER - TY - JOUR AU - Takawa, M. AU - Masuda, K. AU - Kunizaki, M. AU - Daigo, Y. AU - Takagi, K. AU - Iwai, Y. PY - 2011 DA - 2011// TI - Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker JO - Cancer Sci VL - 102 UR - https://doi.org/10.1111/j.1349-7006.2011.01958.x DO - 10.1111/j.1349-7006.2011.01958.x ID - Takawa2011 ER - TY - JOUR AU - Chase, A. AU - Cross, N. C. PY - 2011 DA - 2011// TI - Aberrations of EZH2 in cancer JO - Clin Cancer Res VL - 17 UR - https://doi.org/10.1158/1078-0432.CCR-10-2156 DO - 10.1158/1078-0432.CCR-10-2156 ID - Chase2011 ER - TY - JOUR AU - Richter, G. AU - Plehma, S. AU - Fasana, A. AU - Rosslera, S. AU - Unlandb, R. AU - Bennani-Baitid, I. PY - 2009 DA - 2009// TI - EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation JO - Proc Natl Acad Sci USA VL - 106 UR - https://doi.org/10.1073/pnas.0810759106 DO - 10.1073/pnas.0810759106 ID - Richter2009 ER - TY - JOUR AU - Tirode, F. AU - Surdez, D. AU - Ma, X. AU - Parker, M. AU - Deley, M. C. AU - Bahrami, A. PY - 2014 DA - 2014// TI - Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations JO - Cancer Discov. VL - 4 UR - https://doi.org/10.1158/2159-8290.CD-14-0622 DO - 10.1158/2159-8290.CD-14-0622 ID - Tirode2014 ER - TY - JOUR AU - Svoboda, L. K. AU - Harris, A. AU - Bailey, N. J. AU - Schwentner, R. AU - Tomazou, E. AU - Levetzow, C. PY - 2014 DA - 2014// TI - Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs JO - Epigenetics. VL - 9 UR - https://doi.org/10.4161/15592294.2014.988048 DO - 10.4161/15592294.2014.988048 ID - Svoboda2014 ER - TY - JOUR AU - Ciarapica, R. AU - Salvo, M. AU - Carcarino, E. AU - Bracaglia, G. AU - Adesso, L. AU - Leoncini, P. P. PY - 2014 DA - 2014// TI - The polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx) JO - Oncogene VL - 33 UR - https://doi.org/10.1038/onc.2013.471 DO - 10.1038/onc.2013.471 ID - Ciarapica2014 ER - TY - JOUR AU - Marchesi, I. AU - Fiorentino, F. P. AU - Rizzolio, F. AU - Giordano, A. AU - Bagella, L. PY - 2012 DA - 2012// TI - The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation JO - Cell Cycle VL - 11 UR - https://doi.org/10.4161/cc.22025 DO - 10.4161/cc.22025 ID - Marchesi2012 ER - TY - JOUR AU - Changchien, Y. C. AU - Tátrai, P. AU - Papp, G. AU - Sápi, J. AU - FónyadL, S. z. e. n. d. r. ő. i. M. PY - 2012 DA - 2012// TI - Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2) JO - J Transl Med. VL - 10 UR - https://doi.org/10.1186/1479-5876-10-216 DO - 10.1186/1479-5876-10-216 ID - Changchien2012 ER - TY - JOUR AU - McCabe, M. T. AU - Ott, H. M. AU - Ganji, G. AU - Korenchuk, S. AU - Thompson, C. AU - Aller, G. PY - 2012 DA - 2012// TI - EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations JO - Nature VL - 492 UR - https://doi.org/10.1038/nature11606 DO - 10.1038/nature11606 ID - McCabe2012 ER - TY - JOUR AU - Cote, G. M. AU - Choy, E. PY - 2013 DA - 2013// TI - Role of epigenetic modulation for the treatment of sarcoma JO - Curr Treat Options Oncol VL - 14 UR - https://doi.org/10.1007/s11864-013-0239-3 DO - 10.1007/s11864-013-0239-3 ID - Cote2013 ER - TY - JOUR AU - Micci, F. AU - Gorunova, L. AU - Gatius, S. AU - Matias-Guiu, X. AU - Davidson, B. AU - Heim, S. PY - 2014 DA - 2014// TI - MEAF6/PHF1 is a recurrent gene fusion in endometrial stromal sarcoma JO - Cancer Lett VL - 347 UR - https://doi.org/10.1016/j.canlet.2014.01.030 DO - 10.1016/j.canlet.2014.01.030 ID - Micci2014 ER - TY - JOUR AU - Choi, Y. J. AU - Jung, S. H. AU - Kim, M. S. AU - Baek, I. P. AU - Rhee, J. K. AU - Lee, S. H. PY - 2015 DA - 2015// TI - Genomic landscape of endometrial stromal sarcoma of uterus JO - Oncotarget. VL - 6 ID - Choi2015 ER - TY - JOUR AU - Jain, P. AU - Croce, L. PY - 2016 DA - 2016// TI - Mutations and deletions of PRC2 in prostate cancer JO - Bioessays VL - 38 UR - https://doi.org/10.1002/bies.201500162 DO - 10.1002/bies.201500162 ID - Jain2016 ER - TY - JOUR AU - Lee, W. AU - Teckie, S. AU - Wiesner, T. AU - Ran, L. AU - Prieto Granada, C. N. AU - Lin, M. PY - 2014 DA - 2014// TI - PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors JO - Nat Genet VL - 2014 UR - https://doi.org/10.1038/ng.3095 DO - 10.1038/ng.3095 ID - Lee2014 ER - TY - JOUR AU - Raedt, T. AU - Beert, E. AU - Pasmant, E. AU - Luscan, A. AU - Brems, H. AU - Ortonne, N. PY - 2014 DA - 2014// TI - PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies JO - Nature VL - 514 ID - Raedt2014 ER - TY - JOUR AU - Liu, Y. L. AU - Gao, X. AU - Jiang, Y. AU - Zhang, G. AU - Sun, Z. C. AU - Cui, B. B. PY - 2015 DA - 2015// TI - Expression and clinic pathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer JO - J Cancer Res Clin Oncol VL - 141 UR - https://doi.org/10.1007/s00432-014-1854-5 DO - 10.1007/s00432-014-1854-5 ID - Liu2015 ER - TY - JOUR AU - Jacobsen, B. AU - Muley, T. AU - Meister, M. AU - Dienemann, H. AU - Christensen, I. J. AU - Santoni-Rugiu, E. PY - 2013 DA - 2013// TI - Ly6/uPAR-related protein C4.4A as a marker of solid growth pattern and poor prognosis in lung adenocarcinoma JO - J Thorac Oncol. VL - 8 UR - https://doi.org/10.1097/JTO.0b013e318279d503 DO - 10.1097/JTO.0b013e318279d503 ID - Jacobsen2013 ER - TY - JOUR AU - Kroepil, F. AU - Dulian, A. AU - Vallböhmer, D. AU - Geddert, H. AU - Krieg, A. AU - Vay, C. PY - 2013 DA - 2013// TI - High EpCAM expression is linked to proliferation and lauren classification in gastric cancer JO - BMC Res Notes. VL - 6 UR - https://doi.org/10.1186/1756-0500-6-253 DO - 10.1186/1756-0500-6-253 ID - Kroepil2013 ER - TY - JOUR AU - Melchers, L. J. AU - Bruine de Bruin, L. AU - Schnell, U. AU - Slagter-Menkema, L. AU - Mastik, M. F. AU - Bock, G. H. PY - 2013 DA - 2013// TI - Lack of claudin-7 is a strong predictor of regional recurrence in oral and oropharyngeal squamous cell carcinoma JO - Oral Oncol VL - 49 UR - https://doi.org/10.1016/j.oraloncology.2013.07.008 DO - 10.1016/j.oraloncology.2013.07.008 ID - Melchers2013 ER - TY - JOUR AU - Rao, Z. Y. AU - Cai, M. Y. AU - Yang, G. F. AU - He, L. R. AU - Mai, S. J. AU - Hua, W. F. PY - 2010 DA - 2010// TI - EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients JO - Carcinogenesis VL - 31 UR - https://doi.org/10.1093/carcin/bgq150 DO - 10.1093/carcin/bgq150 ID - Rao2010 ER - TY - JOUR AU - Yamaguchi, H. AU - Hung, M. -. C. PY - 2014 DA - 2014// TI - Regulation and role of EZH2 in Cancer JO - Cancer Res Treat. VL - 46 UR - https://doi.org/10.4143/crt.2014.46.3.209 DO - 10.4143/crt.2014.46.3.209 ID - Yamaguchi2014 ER - TY - JOUR AU - Goldstein, M. AU - Meller, I. AU - Issakov, J. AU - Orr-Urtreger, A. PY - 2006 DA - 2006// TI - Novel genes implicated in embryonal, alveolar, and pleomorphic rhabdomyosarcoma: a cytogenetic and molecular analysis of primary tumors JO - Neoplasia. VL - 8 UR - https://doi.org/10.1593/neo.05829 DO - 10.1593/neo.05829 ID - Goldstein2006 ER - TY - JOUR AU - Wang, C. AU - Liu, Z. AU - Woo, C. W. AU - Li, Z. AU - Wang, L. AU - Wei, J. S. PY - 2012 DA - 2012// TI - EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR JO - Cancer Res VL - 72 UR - https://doi.org/10.1158/0008-5472.CAN-11-0961 DO - 10.1158/0008-5472.CAN-11-0961 ID - Wang2012 ER - TY - JOUR AU - Burdach, S. AU - Plehm, S. AU - Unland, R. AU - Dirksen, U. AU - Borkhardt, A. PY - 2009 DA - 2009// TI - Staege MS Epigenetic maintenance of stemness and malignancy in peripheral neuroectodermal tumors by EZH2 JO - Cell Cycle VL - 8 UR - https://doi.org/10.4161/cc.8.13.8929 DO - 10.4161/cc.8.13.8929 ID - Burdach2009 ER -