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Table 1 Expression of DNA repair related genes in primary GBM cultures and GSC-enriched neurospheres

From: Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs

Gene

p value

Fold change

BRCA1

0.011

3.933

PARP2

0.016

3.285

RPA1

0.017

2.569

LIG1

0.018

2.578

CHEK1

0.018

2.854

MSH3

0.020

2.154

XRCC5

0.021

2.559

CHEK2

0.023

2.971

RAD51

0.024

2.260

TOP2B

0.027

4.195

MSH2

0.035

2.250

XRCC1

0.043

2.324

  1. p value and fold change of the genes that were significantly up-regulated in GSC compared to primary GBM cultures
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Cancer Cell International

ISSN: 1475-2867

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